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Tuesday, November 11, 2014

The Truth About Wellbutrin

Bupropion (Wellbutrin) (bupropion hydrochloride) Film-coated Tablets:

Treats depression and aids in quitting smoking. Also prevents depression caused by seasonal affective disorder (SAD). This medicine is an antidepressant.

Brand names: Wellbutrin, Zyban, Aplenzin, Buproban, Budeprion

Drug Class:  pregnancy class C, low dependency, Wellbutrin (bupropion hydrochloride) is not considered a narcotic in any medical or legal sense.

Drug Description: WELLBUTRIN (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines.

 image It is designated as (±)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1propanone hydrochloride. The molecular weight is 276.2. The molecular formula is C13H18ClNO•HCl. Bupropion hydrochloride powder is white, crystalline, and highly soluble in water. It has a bitter taste and produces the sensation of local anesthesia on the oral mucosa. The structural formula is: WELLBUTRIN is supplied for oral administration as 75-mg (yellow-gold) and 100-mg (red) film-coated tablets. Each tablet contains the labeled amount of bupropion hydrochloride and the inactive ingredients: 75-mg tablet – D&C Yellow No. 10 Lake, FD&C Yellow No. 6 Lake, hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, polyethylene glycol, talc, and titanium dioxide; 100-mg tablet – FD&C Red No. 40 Lake, FD&C Yellow No. 6 Lake, hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, polyethylene glycol, talc, and titanium dioxide.

 

Common Side Effects: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Also possible seizures.

Most common reported:

  • confusion
  • hallucinations
  • irrational fears
  • seizures

 

Abuse Factor: moderate to high. Since it is a mild stimulant close to the amphetamine family, it is abused in the same ways. Snorting, shooting, freebasing, mixing with other narcotics and alcohol. The nice thing about wellbutrin is there is no withdrawal or crashing. It does have a a ceiling on how much you can take. It is a mild effect compared to cocaine and meth, nevertheless often used with other drugs and alcohol. In some countries it is already a controlled substance.

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